Start – Andrew Luck, QB, Colts

The Jaguars have had a dismal start to the season, and after taking a beating by the Seahawks in Seattle last week, they will return home for another tough matchup with Indy. Since it’s at home, the Jaguars might stay in this game a little longer than they did against Seattle, which is nothing but good news for Luck. This means more opportunities to put up numbers. Luck is worth a play this week with a low floor and a high ceiling.

Sit – Eli Manning, QB, Giants

The Giants are a mess right now, and while the younger Manning is known for his statistical ups and downs, a matchup with the high-flying Chiefs in Kansas City this week probably isn’t a game in which he’ll make a rebound. Look for the Giants to struggle in getting the ground game going again and the Chiefs to pressure Manning all game long. It could be another long day for Eli and company.

Start – Isaiah Pead, RB, Rams

Pead has only toted the rock seven times this year, but with Daryl Richardson on the mend and the Rams at home, he’s likely to see the majority of the carries this week. San Francisco has been surprisingly putrid against the run this season, ranking dead last and giving up 139-plus yards and at least two rushing touchdowns in back-to-back games. They play on short rest this Thursday in St. Louis, so look for the Rams to try and establish the run early.

Sit – Jordan Cameron, TE, Browns

The Browns were running on determination last week to shove it in the face of the critics who argued that the Trent Richardson trade more or less ended their season. Unfortunately for them, they really aren’t that good, and chances are last week’s game might have been the brightest point in the season. Cameron was relatively unknown going into this season but has thus far been the sleeper of the year. After a three-touchdown performance last week, I believe the Bengals’ defense, which has been stingy to opposing tight ends this season, will focus more attention on him than other defenses have. Cameron will likely come down to Earth in this one.