Growing up in
Kenya, Sylvia Omulo had two guarantees: falling and infectious diseases.
liked to play,” she said. “Some of my favorite games involved speed and falling
was a consequence of that — the other thing I was prone to was infectious
clinical associate professor in the Paul G. Allen School for Global Animal
Health, presented a lecture on antibiotic resistance in Kenya during the Vice
President for Research Distinguished Lecture on Tuesday.
titled “Antibiotic Use, Antibiotic Resistance, and the Gulf in Between,”
centered around her work with the Centers for Disease Control and Prevention’s
antimicrobial resistance research program in Kenya.
Kenya, Omulo and her team collected data samples from community members in
Kibera, Asembo and hospitals in Mbagathi, Siaya, Omulo said. Her team used the
samples to estimate risk factors of people developing multidrug resistant
organisms, or germs resistant to antibiotics.
researchers found a high prevalence of MDROs in Extended-Spectrum
Beta-lactamase enzymes in hospitals in Mbagathi at over 90 percent among adults
and 80 percent among children. These enzymes can cause antibiotics not to work
for treating bacterial infections, especially among urine infections.
58.9 percent of community members had ESBLs, and 58.1 percent of children were found to have the enzyme
preliminary data so don’t read too much into it,” Omulo said.
is still needed to get definitive answers for risk factors that make MDROs
prevalent, she said. However, she said patients who have had a tube placed in
them for medical purposes have a greater risk of developing ESBLs.
use within a two-week span, a history of tumors or cancer, and brain or spinal
cord diseases also are risk factors to other MDROS that were tested, she said.
Although these MDROS were not as prevalent as ESBLs in their study.
Burbick, clinical associate professor in the College of Veterinary Medicine,
said the data shown for ESBL’s would be frightening for hospitals if it held up
in further testing.
devastate your hospital,” Burbick said.
She said it is
important to make sure people understand how researchers perform their
scientific studies, and that the data would likely change after further
do their science] It’s the meat and potatoes, it’s kind of critical,” she said.
her team’s collaboration with the CDC put them through an extensive validation
process, and their early findings should be treated as preliminary data.
She said to
reduce the demands for antibiotics,
communities must invest in high-quality antibiotic practices, as well as
solving environmental issues that may lead to greater risk of transmitting
to get an antibiotic, seek a doctor’s intervention first,” Omulo said.
Mietchen, WSU doctoral student in the Paul G. Allen School for Global Animal
Health, said the lecture was informative regarding the issues of microbial data
public health point-of-view,” he said. “It is useful to see studies that are
being conducted around the world.”
Christopher Keane, vice president for research, said Omulo will present this lecture again in Spokane on March 11.